Can I take 10B Probiotic with DIM?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

10B Probiotic
+
DIM

Short answer

We found no documented interaction between Probiotic and DIM in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Probiotic

What it is: Live microorganisms, mostly bacteria, that may benefit health when taken in large enough amounts. They work mainly in the gut.

What the research says: Effects depend on the specific strain, and many probiotic products haven't been studied.

Cautions

  • Probiotics have a long record of safe use; healthy people may get some gas.
  • They may not be safe for people who are seriously ill or have a weakened immune system.

In Holitro: 10B Probiotic

Source: NIH Office of Dietary Supplements: Probiotics: Fact Sheet for Consumers (updated November 2025)

DIM (diindolylmethane)

What it is: A compound formed from vegetables like broccoli and cabbage, sold for estrogen balance.

What the research says: It changes how estrogen is broken down, and lab studies suggest anticancer effects, but human data are limited. There's no evidence for 'detox' claims.

Cautions

  • Not for pregnancy, trying to conceive or breastfeeding, because of possible hormone effects.
  • Rare reports include vision problems after very high use, and rash.

Medicines to check

  • Birth control pills: check with a clinician first
  • Many prescription drugs processed by the liver: DIM may make them less effective

In Holitro: DIM (300 mg per capsule)

Source: Memorial Sloan Kettering Cancer Center, About Herbs: Diindolylmethane (updated December 2023)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

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Balancing dosages across multiple different bottles is risky, inefficient, and expensive. 10B Probiotic is already lab-dosed and delivered daily in our Gut Pack — one less bottle to manage.

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