Can I take Alpha Lipoic Acid with Glutamine?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

Alpha Lipoic Acid
+
Glutamine

Short answer

We found no documented interaction between Alpha-lipoic acid and Glutamine in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Alpha-lipoic acid

What it is: An antioxidant the body makes and uses to produce energy.

What the research says: It's used for diabetic nerve pain, and studies suggest it can improve insulin sensitivity.

Cautions

  • It can cause nausea, vomiting and low blood sugar.
  • Rare cases of a condition causing sudden low blood sugar have been reported.

Medicines to check

  • Diabetes medicines: it can lower blood sugar further

In Holitro: Alpha Lipoic Acid (500 mg per capsule)

Source: Memorial Sloan Kettering Cancer Center, About Herbs: Alpha-Lipoic Acid (updated July 2026)

Glutamine

What it is: An amino acid the body makes and uses for energy and to build protein.

What the research says: It has little or no benefit for strength or recovery. It's studied mainly in cancer care and after surgery.

Cautions

  • Studies report no side effects at up to 45 g a day for several weeks; reported side effects elsewhere include headache and nausea.
  • Don't confuse it with glutamate, which is a different substance.

In Holitro: Glutamine (750 mg per capsule)

Sources: NIH Office of Dietary Supplements: Dietary Supplements for Exercise and Athletic Performance (updated March 2021); Memorial Sloan Kettering Cancer Center, About Herbs: Glutamine (updated September 2026)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

Stop Guessing Your Dosages.

Balancing dosages across multiple different bottles is risky, inefficient, and expensive. Alpha Lipoic Acid is already lab-dosed in our Antioxidant Pack, and Glutamine is in our Gut Pack — either way, that’s one less bottle to manage.

Shop Antioxidant Pack