Short answer

We found no documented interaction between Alpha-lipoic acid and Tribulus terrestris in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Alpha-lipoic acid

What it is: An antioxidant the body makes and uses to produce energy.

What the research says: It's used for diabetic nerve pain, and studies suggest it can improve insulin sensitivity.

Cautions

• It can cause nausea, vomiting and low blood sugar.
• Rare cases of a condition causing sudden low blood sugar have been reported.

Medicines to check

• Diabetes medicines: it can lower blood sugar further

In Holitro: Alpha Lipoic Acid (500 mg per capsule)

Source: Memorial Sloan Kettering Cancer Center, About Herbs: Alpha-Lipoic Acid (updated July 2026)

Tribulus terrestris

What it is: A plant sold with claims that it raises testosterone.

What the research says: The few studies on strength or muscle found no benefit.

Cautions

• It hasn't been studied enough to know whether it's safe; high doses damaged the heart, liver and kidneys in animals.
• Sports-medicine experts advise against supplements claimed to boost testosterone.

Medicines to check

• Talk to your clinician if you take any medicine

In Holitro: Tribulus (500 mg per capsule)

Source: NIH Office of Dietary Supplements: Dietary Supplements for Exercise and Athletic Performance (updated March 2021)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.