Can I take Biotin with Zinc?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

Biotin
+
Zinc

Short answer

We found no documented interaction between Biotin and Zinc in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Biotin

What it is: A B vitamin that helps turn the food you eat into energy.

What the research says: It's widely sold for hair, skin and nails, but there's little evidence for that. A few small studies found harder nails in people with brittle nails.

Cautions

  • High-dose biotin can make some lab tests wrong, including thyroid hormone tests. Tell your clinician before a blood test.

Medicines to check

  • Long-term anti-seizure medicines can lower biotin levels

In Holitro: Biotin 5000mcg (5000 mcg per capsule)

Source: NIH Office of Dietary Supplements: Biotin: Fact Sheet for Consumers (updated January 2021)

Zinc

What it is: An essential mineral for the immune system, wound healing, taste, and making DNA and proteins.

What the research says: Zinc is needed for normal immune function; it's commonly taken to make sure intake is adequate.

Cautions

  • Adults shouldn't exceed 40 mg a day from all sources unless under medical care.
  • Too much for a long time can lower copper levels and immunity.
  • Very high doses can reduce magnesium absorption.

Medicines to check

  • Quinolone and tetracycline antibiotics: take the antibiotic at least 2 hours before or 4 to 6 hours after zinc
  • Penicillamine: take at least 1 hour apart
  • Thiazide diuretics can lower zinc levels

In Holitro: Zinc (25 mg per capsule)

Source: NIH Office of Dietary Supplements: Zinc: Fact Sheet for Consumers (updated October 2022)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

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