Can I take Choline with Green Tea Extract?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

Choline
+
Green Tea Extract

Short answer

We found no documented interaction between Choline and Green tea extract in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Choline

What it is: A nutrient the brain and nerves need for memory, mood and muscle control; it also builds cell membranes.

What the research says: Its effect on heart health is unclear: some research points to benefit and some to higher risk.

Cautions

  • Adults shouldn't exceed 3,500 mg a day.
  • Too much can cause fishy body odor, vomiting, sweating, low blood pressure and liver damage.

Medicines to check

  • It isn't known to interact with any medicines

In Holitro: Choline (420 mg per capsule)

Source: NIH Office of Dietary Supplements: Choline: Fact Sheet for Consumers (updated June 2022)

Green tea extract

What it is: A concentrated extract of green tea leaves, rich in catechins such as EGCG. It contains caffeine.

What the research says: Catechins and caffeine may have a modest effect on weight, and it lowered LDL cholesterol a little. Cancer results are inconsistent.

Cautions

  • Extracts can cause nausea, constipation, stomach discomfort and higher blood pressure.
  • Liver injury has been reported, mainly with extract capsules; a gene variant found in 5 to 15% of Americans raises the risk.

Medicines to check

  • Nadolol (a beta-blocker): green tea can lower its levels
  • Atorvastatin (a statin) and raloxifene (an osteoporosis drug)

In Holitro: Green Tea Extract 500mg (500 mg per capsule)

Source: NIH National Center for Complementary and Integrative Health: Green Tea: Usefulness and Safety (updated February 2025)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack β€” free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

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