Understanding the interactions, benefits, and safety of combining these two powerful supplements.
We found no documented interaction between Probiotic and Arginine in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.
What it is: Live microorganisms, mostly bacteria, that may benefit health when taken in large enough amounts. They work mainly in the gut.
What the research says: Effects depend on the specific strain, and many probiotic products haven't been studied.
In Holitro: 10B Probiotic
Source: NIH Office of Dietary Supplements: Probiotics: Fact Sheet for Consumers (updated November 2025)
What it is: An amino acid the body makes and gets from protein foods. The body turns it into nitric oxide, which widens blood vessels.
What the research says: There's little evidence it improves strength, exercise performance or recovery.
In Holitro: Arginine (500 mg per capsule)
Sources: NIH Office of Dietary Supplements: Dietary Supplements for Exercise and Athletic Performance (updated March 2021); Memorial Sloan Kettering Cancer Center, About Herbs: Arginine (updated February 2022)
Check with your doctor or pharmacist, especially if you take medication.
Check your stack — freeEducational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.
Balancing dosages across multiple different bottles is risky, inefficient, and expensive. 10B Probiotic is already lab-dosed and delivered daily in our Gut Pack — one less bottle to manage.
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