Short answer

We found no direct interaction between Alpha-lipoic acid and Cordyceps in the sources below, but they share a caution.

Both have a note about diabetes medicines (see each one below).

Both may lower blood sugar, so the effects could add up, especially with diabetes medicine.

Alpha-lipoic acid

What it is: An antioxidant the body makes and uses to produce energy.

What the research says: It's used for diabetic nerve pain, and studies suggest it can improve insulin sensitivity.

Cautions

• It can cause nausea, vomiting and low blood sugar.
• Rare cases of a condition causing sudden low blood sugar have been reported.

Medicines to check

• Diabetes medicines: it can lower blood sugar further

In Holitro: Alpha Lipoic Acid (500 mg per capsule)

Source: Memorial Sloan Kettering Cancer Center, About Herbs: Alpha-Lipoic Acid (updated July 2026)

Cordyceps

What it is: A fungus that grows on moth caterpillars, used in traditional Chinese medicine for energy and immunity.

What the research says: Some studies looked at kidney function in transplant and diabetes patients, but reviews question the quality of the evidence. Most research is in the lab.

Cautions

• No major side effects have been reported.

Medicines to check

• Insulin and other blood-sugar-lowering medicines: cordyceps may lower blood sugar too
• Blood thinners such as warfarin: it may raise bleeding risk

In Holitro: Cordyceps (500 mg per capsule)

Source: Memorial Sloan Kettering Cancer Center, About Herbs: Cordyceps (updated February 2022)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.