Short answer

We found no documented interaction between Alpha-lipoic acid and Forskolin in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Alpha-lipoic acid

What it is: An antioxidant the body makes and uses to produce energy.

What the research says: It's used for diabetic nerve pain, and studies suggest it can improve insulin sensitivity.

Cautions

• It can cause nausea, vomiting and low blood sugar.
• Rare cases of a condition causing sudden low blood sugar have been reported.

Medicines to check

• Diabetes medicines: it can lower blood sugar further

In Holitro: Alpha Lipoic Acid (500 mg per capsule)

Source: Memorial Sloan Kettering Cancer Center, About Herbs: Alpha-Lipoic Acid (updated July 2026)

Forskolin (Coleus forskohlii)

What it is: An extract of a plant in the mint family; forskolin is its active compound.

What the research says: One small 12-week trial in 30 overweight men found less body fat and higher free testosterone. Larger studies are lacking.

Cautions

• We didn't find a reliable safety review.

Medicines to check

• Talk to your clinician if you take any medicine

In Holitro: Forslean (500 mg per capsule)

Source: PubMed review: Forskolin and body composition in overweight men (2005) (updated August 2005)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.