Can I take Arginine with Green Tea Extract?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

Arginine
+
Green Tea Extract

Short answer

We found no direct interaction between Arginine and Green tea extract in the sources below, but they share a caution.

Both have a note about blood-pressure medicines (see each one below).

Arginine

What it is: An amino acid the body makes and gets from protein foods. The body turns it into nitric oxide, which widens blood vessels.

What the research says: There's little evidence it improves strength, exercise performance or recovery.

Cautions

  • Up to 9 g a day seems safe for days to weeks; more can cause stomach upset.
  • It can lower blood pressure slightly.

Medicines to check

  • Blood-pressure medicines: arginine can lower blood pressure too

In Holitro: Arginine (500 mg per capsule)

Sources: NIH Office of Dietary Supplements: Dietary Supplements for Exercise and Athletic Performance (updated March 2021); Memorial Sloan Kettering Cancer Center, About Herbs: Arginine (updated February 2022)

Green tea extract

What it is: A concentrated extract of green tea leaves, rich in catechins such as EGCG. It contains caffeine.

What the research says: Catechins and caffeine may have a modest effect on weight, and it lowered LDL cholesterol a little. Cancer results are inconsistent.

Cautions

  • Extracts can cause nausea, constipation, stomach discomfort and higher blood pressure.
  • Liver injury has been reported, mainly with extract capsules; a gene variant found in 5 to 15% of Americans raises the risk.

Medicines to check

  • Nadolol (a beta-blocker): green tea can lower its levels
  • Atorvastatin (a statin) and raloxifene (an osteoporosis drug)

In Holitro: Green Tea Extract 500mg (500 mg per capsule)

Source: NIH National Center for Complementary and Integrative Health: Green Tea: Usefulness and Safety (updated February 2025)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack β€” free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

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