Can I take Berberine with Chlorella?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

Berberine
+
Chlorella

Short answer

We found no documented interaction between Berberine and Chlorella in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Berberine

What it is: A compound from plants such as barberry and goldenseal, used in Chinese and Ayurvedic medicine.

What the research says: It may lower cholesterol, triglycerides and blood sugar, but the effect may be small and lifestyle changes are still needed.

Cautions

  • Mild side effects can include appetite loss, upset stomach, diarrhea, constipation and rash.
  • Not for pregnancy or breastfeeding: it may harm newborns.

Medicines to check

  • Immune-suppressing drugs such as tacrolimus or cyclosporin: berberine may raise their levels
  • Some diabetes drugs (sulfonylureas)
  • Many prescription drugs processed by the liver: berberine may make them less effective
  • Bosutinib (a cancer drug)

In Holitro: Berberine 500mg (500 mg per capsule)

Source: Memorial Sloan Kettering Cancer Center, About Herbs: Berberine (updated June 2023)

Chlorella

What it is: A green freshwater alga sold as a supplement.

What the research says: A review of 10 trials found modest drops in total and LDL cholesterol. Only 2 of those trials checked what the supplements actually contained.

Cautions

  • That review didn't assess safety, and we didn't find a reliable safety review.

Medicines to check

  • Talk to your clinician if you take any medicine

In Holitro: Chlorella (500 mg per capsule)

Source: PubMed review: Chlorella vulgaris and lipid profile: meta-analysis (2022) (updated March 2022)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack β€” free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

Stop Guessing Your Dosages.

Balancing dosages across multiple different bottles is risky, inefficient, and expensive. Taking too much of one can blunt the absorption of the other.

Holitro completely solves this. We combine synergistic ingredients into one perfectly dosed daily pack, scientifically formulated for maximum absorption.

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