Can I take Biotin with Quercetin?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

Biotin
+
Quercetin

Short answer

We found no documented interaction between Biotin and Quercetin in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Biotin

What it is: A B vitamin that helps turn the food you eat into energy.

What the research says: It's widely sold for hair, skin and nails, but there's little evidence for that. A few small studies found harder nails in people with brittle nails.

Cautions

  • High-dose biotin can make some lab tests wrong, including thyroid hormone tests. Tell your clinician before a blood test.

Medicines to check

  • Long-term anti-seizure medicines can lower biotin levels

In Holitro: Biotin 5000mcg (5000 mcg per capsule)

Source: NIH Office of Dietary Supplements: Biotin: Fact Sheet for Consumers (updated January 2021)

Quercetin

What it is: A plant compound found in apples, onions and tea; the most common flavonoid in the diet.

What the research says: It hasn't been shown to treat any disease. Its anti-inflammatory effects come from lab studies; in athletes, any performance benefits were small.

Cautions

  • No side effects were seen in athletes taking about 1,000 mg a day, but it hasn't been studied enough to know it's safe.

Medicines to check

  • Some prescription drugs processed by the liver: it may increase their side effects (lab data)
  • Losartan (a blood-pressure drug) and tamoxifen: animal or lab data only

In Holitro: Quercetin (500 mg per capsule)

Sources: Memorial Sloan Kettering Cancer Center, About Herbs: Quercetin (updated October 2023); NIH Office of Dietary Supplements: Dietary Supplements for Exercise and Athletic Performance (updated March 2021)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

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