Short answer

We found no documented interaction between Choline and Multivitamin in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Choline

What it is: A nutrient the brain and nerves need for memory, mood and muscle control; it also builds cell membranes.

What the research says: Its effect on heart health is unclear: some research points to benefit and some to higher risk.

Cautions

• Adults shouldn't exceed 3,500 mg a day.
• Too much can cause fishy body odor, vomiting, sweating, low blood pressure and liver damage.

Medicines to check

• It isn't known to interact with any medicines

In Holitro: Choline (420 mg per capsule)

Source: NIH Office of Dietary Supplements: Choline: Fact Sheet for Consumers (updated June 2022)

Multivitamin

What it is: A combination of vitamins and minerals in one supplement.

What the research says: A multivitamin raises your daily nutrient intake; it's hard to show it prevents disease. It can't replace a varied diet.

Cautions

• A basic multivitamin is unlikely to cause harm, but check your total intake if you also take other supplements or fortified foods.
• Smokers should avoid multivitamins with large amounts of beta-carotene or vitamin A.

Medicines to check

• Warfarin: talk to your clinician before any supplement with vitamin K

In Holitro: Multivitamin

Source: NIH Office of Dietary Supplements: Multivitamin/mineral Supplements: Fact Sheet for Consumers (updated February 2024)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.