Can I take Citrulline with Taurine?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

Citrulline
+
Taurine

Short answer

We found no documented interaction between Citrulline and Taurine in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Citrulline

What it is: An amino acid the body makes. The kidneys turn most of it into arginine, and then nitric oxide.

What the research says: Research on it as a performance supplement is limited and mixed.

Cautions

  • There isn't enough research to know whether it's safe; some people report stomach discomfort.

In Holitro: Citrulline (500 mg per capsule)

Source: NIH Office of Dietary Supplements: Dietary Supplements for Exercise and Athletic Performance (updated March 2021)

Taurine

What it is: An amino acid from meat, dairy and seafood that the body can also make; it's involved in heart, muscle and nerve function.

What the research says: A few studies suggest it may lower blood pressure. It didn't improve blood sugar in overweight men, and exercise results are mixed.

Cautions

  • Very large amounts of taurine together with alcohol or caffeine (as in energy drinks) have been linked to severe reactions, including deaths.

Medicines to check

  • Blood-pressure medicines: taurine may add to their effect

In Holitro: Taurine (800 mg per capsule)

Source: Memorial Sloan Kettering Cancer Center, About Herbs: Taurine (updated August 2023)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack β€” free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

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