Short answer

We found no direct interaction between CoQ10 and Resveratrol in the sources below, but they share a caution.

Both have a note about blood thinners such as warfarin (see each one below).

CoQ10

What it is: A compound the body makes, found at high levels in the heart, liver and kidneys.

What the research says: Studies on heart disease are inconclusive. Overall, it doesn't seem to relieve muscle pain from statins, and it probably doesn't lower blood pressure meaningfully.

Cautions

• No serious side effects reported; it can cause mild insomnia or stomach upset.

Medicines to check

• Warfarin (blood thinner) and insulin
• Some cancer treatments: check with your care team

In Holitro: CoQ10 (200 mg per capsule)

Source: NIH National Center for Complementary and Integrative Health: Coenzyme Q10 (updated January 2019)

Resveratrol

What it is: A compound found in grapes, red wine, peanuts and berries, sold as an anti-aging supplement.

What the research says: Anti-aging effects have been seen in yeast, not people. Reviews and recent trials found no benefit for memory or thinking.

Cautions

• High doses can cause nausea, gas, stomach pain and diarrhea.

Medicines to check

• Blood thinners and antiplatelet drugs: it may raise bleeding risk
• Some prescription drugs processed by the liver

In Holitro: Resveratrol (250 mg per capsule)

Source: Memorial Sloan Kettering Cancer Center, About Herbs: Resveratrol (updated February 2023)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.