Can I take Creatine with Green Tea Extract?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

Creatine
+
Green Tea Extract

Short answer

We found no documented interaction between Creatine and Green tea extract in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Creatine

What it is: A compound stored in muscle that supplies energy for short, intense effort. The body makes about 1 g a day.

What the research says: Creatine can increase strength and power for repeated short bursts like sprinting and lifting, but helps little with endurance exercise. Studies typically used 3 to 5 g a day after a loading phase; creatine monohydrate is the most studied form.

Cautions

  • Considered safe for healthy adults for weeks to months, and it seems safe for years.
  • It usually causes some weight gain from water retention; rarely cramps or stomach upset.

In Holitro: Creatine (750 mg per capsule)

Source: NIH Office of Dietary Supplements: Dietary Supplements for Exercise and Athletic Performance (updated March 2021)

Green tea extract

What it is: A concentrated extract of green tea leaves, rich in catechins such as EGCG. It contains caffeine.

What the research says: Catechins and caffeine may have a modest effect on weight, and it lowered LDL cholesterol a little. Cancer results are inconsistent.

Cautions

  • Extracts can cause nausea, constipation, stomach discomfort and higher blood pressure.
  • Liver injury has been reported, mainly with extract capsules; a gene variant found in 5 to 15% of Americans raises the risk.

Medicines to check

  • Nadolol (a beta-blocker): green tea can lower its levels
  • Atorvastatin (a statin) and raloxifene (an osteoporosis drug)

In Holitro: Green Tea Extract 500mg (500 mg per capsule)

Source: NIH National Center for Complementary and Integrative Health: Green Tea: Usefulness and Safety (updated February 2025)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

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