Short answer

We found no documented interaction between Forskolin and Vitamin C in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Forskolin (Coleus forskohlii)

What it is: An extract of a plant in the mint family; forskolin is its active compound.

What the research says: One small 12-week trial in 30 overweight men found less body fat and higher free testosterone. Larger studies are lacking.

Cautions

• We didn't find a reliable safety review.

Medicines to check

• Talk to your clinician if you take any medicine

In Holitro: Forslean (500 mg per capsule)

Source: PubMed review: Forskolin and body composition in overweight men (2005) (updated August 2005)

Vitamin C

What it is: An antioxidant vitamin the body needs to make collagen, absorb iron from plant foods and support the immune system.

What the research says: Vitamin C is essential; supplements make sure you get enough if your diet falls short.

Cautions

• Adults shouldn't exceed 2,000 mg a day; too much can cause diarrhea, nausea and cramps.
• People with hemochromatosis should avoid high doses.

Medicines to check

• Chemotherapy and radiation: check with your care team first
• In one study, antioxidants including vitamin C reduced the benefit of a statin plus niacin

In Holitro: Vitamin C (1000 mg per capsule)

Source: NIH Office of Dietary Supplements: Vitamin C: Fact Sheet for Consumers (updated March 2021)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.