Can I take Glycine with Omega 3?

Understanding the interactions, benefits, and safety of combining these two powerful supplements.

Glycine
+
Omega 3

Short answer

We found no documented interaction between Glycine and Omega-3 in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Glycine

What it is: An amino acid the body makes; it's a building block of creatine, glutathione and collagen.

What the research says: Some studies suggest it may improve sleep quality and recovery, but reviews say more good human trials are needed.

Cautions

  • No major safety concerns are reported at supplement doses; human research is limited.

Medicines to check

  • Talk to your clinician if you take any medicine

In Holitro: Glycine (850 mg per capsule)

Sources: PubMed review: An Update of the Promise of Glycine Supplementation (Sports, 2024) (updated September 2024); PubMed review: Multifarious Beneficial Effect of Glycine: A Review (2017) (updated March 2017)

Omega-3 (fish oil)

What it is: Fats (EPA and DHA) found in fish that are part of every cell membrane and matter for the heart, brain and eyes.

What the research says: EPA and DHA lower triglycerides. Heart experts recommend eating fish; they don't recommend omega-3 supplements for people at low heart risk.

Cautions

  • The FDA advises no more than 5 g a day of EPA plus DHA from supplements.
  • Side effects are usually mild: fishy taste, heartburn, nausea, loose stools.

Medicines to check

  • Warfarin and other blood thinners: high doses may raise bleeding risk

In Holitro: Omega 3 1000mg (1000 mg per capsule)

Source: NIH Office of Dietary Supplements: Omega-3 Fatty Acids: Fact Sheet for Consumers (updated July 2022)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.

Already Combined For You

Glycine and Omega 3 don’t need separate bottles — both are already dosed together, every day, in our Stress Pack.

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