Short answer

We found no documented interaction between Hyaluronic acid and Triphala in the sources below. That isn't proof the combination is right for you: check each one's cautions, and ask your pharmacist if you take medication.

Hyaluronic acid

What it is: A substance found naturally in skin and joints; taken by mouth for skin hydration.

What the research says: A review of 7 trials found better skin hydration and elasticity and shallower wrinkles. The trials were small and varied, so larger studies are needed.

Cautions

• The review didn't assess safety, and we didn't find a reliable safety review.

Medicines to check

• Talk to your clinician if you take any medicine

In Holitro: Hyaluronic Acid (60 mg per capsule)

Source: PubMed review: Oral hyaluronic acid and skin: meta-analysis (2025) (updated September 2025)

Triphala

What it is: A traditional Ayurvedic blend of three dried fruits (amalaki, bibhitaki and haritaki), used mainly for digestion.

What the research says: It's traditionally used as a gentle laxative. Most other proposed benefits come from lab and animal studies, not good human trials.

Cautions

• There's little human safety research. Because it acts as a laxative, loose stools are possible.

Medicines to check

• Talk to your clinician if you take any medicine

In Holitro: Triphala (500 mg per capsule)

Source: PubMed review: Therapeutic Uses of Triphala in Ayurvedic Medicine (2017) (updated July 2017)

Check with your doctor or pharmacist, especially if you take medication.

Check your stack — free

Educational information only, not medical advice. This reflects general ingredient overlap, not a personalized safety review. Always check with your doctor or pharmacist before combining supplements, especially if you take medication, are pregnant or nursing, or manage a health condition. These statements have not been evaluated by the FDA.